A support vector machine for identification of single-nucleotide polymorphisms from next-generation sequencing data
نویسندگان
چکیده
منابع مشابه
A support vector machine for identification of single-nucleotide polymorphisms from next-generation sequencing data
MOTIVATION Accurate determination of single-nucleotide polymorphisms (SNPs) from next-generation sequencing data is a significant challenge facing bioinformatics researchers. Most current methods use mechanistic models that assume nucleotides aligning to a given reference position are sampled from a binomial distribution. While such methods are sensitive, they are often unable to discriminate e...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2013
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btt172